N-Acetyl L-Tyrosine vs L-Tyrosine
N-Acetyl L-Tyrosine (NALT) is the more bioavailable form of the non-essential amino acid L-Tyrosine. It is more readily absorbed by the body, and in theory, has stronger nootropic effects. NALT breaks down into tyrosine in the kidneys.
L-Tyrosine is found in protein sources such as meat, eggs, beans, and cheese. It converts in the brain to L-DOPA, a precursor to neurotransmitters such as dopamine, epinephrine, and norepinephrine. Dopamine plays an important role in pleasure, focus, and motivation. Tyrosine is also involved in protein synthesis.
N-acetyl L-tyrosine seems to contribute to a perceived reduction in stress.* It promotes a positive mood by improving the synthesis of dopamine, a neurotransmitter that plays a role in the way we feel pleasure. NALT can help to regulate mood during times of increased stress by regulating the balance of dopamine and norepinephrine in the brain.
As a cognitive supplement, L-tyrosine studies listed on Examine.com show that it promotes working memory.*
NALT is often preferred by some over L-tyrosine because it is more easily absorbed in the body due to its increased solubility over normal L-tyrosine.
PureBulk’s NALT powder is also 100% pure and free of sugar, gluten, and additives.
NALT Interactions and Synergies
N-acetyl L-tyrosine can potentiate some stimulants and may interact with MAOIs.* Consult with a physician before taking NALT if you are on any medications. Do not take NALT if you have low blood pressure or certain thyroid conditions.
When and How Much to Take
For sports performance stress reduction, NALT is best taken 30 to 60 minutes before exercise.
Take up to around 350mg, but start with 100mg to assess tolerance. Do not take more than 400mg daily as N-acetyl L-tyrosine has a long half-life. It’s water-soluble, so you don’t have to take NALT with food.
N-acetyl L-tyrosine has a slightly sour, citrus-like taste. It’s somewhat similar to citrulline malate or ascorbic acid in taste and goes well with juice, or by itself in plain water or with sweetener. Despite it’s citrus taste, the dosage isn’t large enough to influence the overall taste of your workout shake.
200-400mg of N-acetyl L-tyrosine has helped me start and plow through workouts when I wasn’t in the mood (leg days). I’ve found this is the primary benefit and it’s likely why it’s included in some pre workouts.
Anecdotally, there is a perceived reduction in stress* and workout intensity after taking NALT, compared to a workouts without NALT, but with the same weight. So you’re not likely going to lift more, but you may hate it less.
Should You Cycle NALT?
I’m including this in the ‘opinion’ section since I couldn’t find a solid source in cycling L-tyrosine or N-acetyl L-tyrosine. Because this ingredient is in C4 and other popular pre workouts, it’s safe to assume there are individuals taking this almost daily, depending on their weekly workout split. However, it’s best to cycle NALT to reduce your tolerance.